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Weighing the risk of GLP-1 treatment in older adults: Should we be concerned about sarcopenic obesity? - ScienceDirect
In this case, semaglutide was administered subcutaneously once weekly, starting at 0.25 mg for 4 weeks, increasing to 0.5 mg for another 4 weeks, and then maintained at 1.0 mg weekly, with dose adjustments allowed based on tolerability and participant-specific needs
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Clinical trials, including the SURPASS program, have shown that tirzepatide achieves greater reductions in body weight (up to 22.5%) and HbA1c levels compared to GLP-1 monotherapy with semaglutide [22, 23]
